Arrhythmogenic Right Ventricular Cardiomyopathy: Toward a Modern Clinical and Genomic Understanding.
نویسندگان
چکیده
منابع مشابه
Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia
Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is characterized by progressive, fibrofatty replacement of the myocardium, ventricular arrhythmia, sudden death, and progressive heart failure. ARVC/D may be an important cause of syncope, ventricular arrhythmias, electrocardiogram (ECG) abnormalities and/or non-ischemic wall motion abnormalities. Some patients, however, do not ...
متن کاملArrhythmogenic Ventricular Dysplasia/Cardiomyopathy: Insights from the Rationale of Disease Nomenclature and Clinical Perspectives
“Arrhythmogenic right ventricular dysplasia” (ARVD), a heart muscle disorder characterized by the presence of fibro-fatty tissue and ventricular electrical vulnerability related to sudden death, was first described in 1977 by a French team. Since then, other terms such as “arrhythmogenic right ventricular cardiomyopathy” (ARVC), “arrhythmogenic cardiomyopathy” (AC), “left-dominant arrhythmogeni...
متن کاملArrhythmogenic right ventricular cardiomyopathy in a 52-year-old man – clinical presentation mimicking an acute coronary syndrome
Arrhythmogenic right ventricular cardiomyopathy is an infrequently diagnosed, genetically determined disease that leads to significant clinical consequences, including progressive heart failure and ventricular arrhythmias accounting for sudden cardiac death. We report the case of a 52-year-old patient who presented with ventricular tachycardia and features of an acute coronary syndrome. However...
متن کاملThe genetic background of arrhythmogenic right ventricular cardiomyopathy
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by degeneration of the right ventricle and ventricular tachycardia originating from the right ventricle. Additionally, the disease is an inherited cardiomyopathy that mainly follows the autosomal dominant pattern. More than 10 genes have been reported as causative genes for ARVC, and more than half of ARVC patients carry mu...
متن کاملGuidelines for genetic testing of inherited cardiac disorders.
Inherited gene variants have been implicated increasingly in cardiac disorders but the clinical impact of these discoveries has been variable. For some disorders, such as familial hypertrophic cardiomyopathy, long QT syndrome, and familial hypercholesterolaemia, genetic testing has a high yield and has become an integral part of family management. For other disorders, including dilated cardiomy...
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عنوان ژورنال:
- Circulation. Cardiovascular genetics
دوره 8 3 شماره
صفحات -
تاریخ انتشار 2015